منابع مشابه
Heritability of testis size.
Testis size is an important feature of male pubertal development. The genetic and environmental contributions to variation in human testis size have hardly been studied. We estimated the heritability of human testicular size in a group of mono- and dizygotic twins and their non-twin brothers (145 twins and 20 brothers from 95 families). Participants were 18 years old on average and all had reac...
متن کاملInterspecies comparisons of micronutrient requirements: metabolic vs. absolute body size.
In the paper by Prohaska and Brokate (1), “Timing of Perinatal Copper Deficiency in Mice Influences Offspring Survival,” a key observation is made that copper deficiency can have an important and negative effect on the survival of offspring. Further, several approaches are used to extrapolate from data derived from mice to potential application in humans. In this commentary, we wish to address ...
متن کاملOn the relative sample size required for multiple comparisons.
Multiple comparisons are commonly made in epidemiologic and genetic research. How to appropriately adjust for multiple comparisons remains a controversial issue. This note demonstrates, however, that large increases in the number of comparisons has a limited effect on the sample size required to maintain an experimentwise alpha-level. In particular, the relative sample size required increases o...
متن کاملSize selective dustiness and exposure; simulated workplace comparisons.
A simulated workplace study was conducted to investigate the relation between inhalation exposure and dustiness determined with a rotating drum dustiness tester. Three powders were used in the study, i.e. magnesium stearate, representing a very dusty powder, and aluminium oxide and calcium carbonate, representing low and very low dusty powders, respectively. Two scenarios of handling small volu...
متن کاملSample Size Growth with an Increasing Number of Comparisons
An appropriate sample size is crucial for the success of many studies that involve a large number of comparisons. Sample size formulas for testing multiple hypotheses are provided in this paper. They can be used to determine the sample sizes required to provide adequate power while controlling familywise error rate or false discovery rate, to derive the growth rate of sample size with respect t...
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ژورنال
عنوان ژورنال: Nature
سال: 1987
ISSN: 0028-0836,1476-4687
DOI: 10.1038/325396a0